MK-677 is , while it's Molecular Formula is CH 4 O 3 S*C 27 H 36 N 4 O 5 S. Growthhormone releasing factor.MK-677 is a potent, non-peptide ghrelin receptor agonist.

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MK-677

Q: What is MK-677 (159752-10-0) used for?

MK-677?(also known as ibutamoren),?promotes the secretion of the growth hormone (GH)?and?increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone?ghrelin?and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on?appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

CasNo：159752-10-0
Molecular Formula：C28H40N4O8S2
Purity：
Molecular Weight：624.78

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What is the MK-677 ?

MK-677 (ibutamoren) is an orally active growth hormone secretagogue, while it's Molecular Formula is CH₄O₃S*C₂₇H₃₆N₄O₅S. Also of note, Nutrabol (MK 677) although technically a growth hormone secretagogue and not a SARM, was classified as a SARM in some studies.

What is the CAS number for MK-677 ?

The CAS number of MK-677 is 159752-10-0.

More information of MK-677 159752-10-0 are:

Synonyms	2-Amino-N-((R)-2-(benzyloxy)-1-((1-(methylsulfonyl)spiro(indoline-3,4'-piperidin)-1'-yl)carbonyl)ethyl)-2-methyl-propionamide monomethanesulfonate;2-Amino-N-((R)-2-(benzyloxy)-1-((1-(methylsulfonyl)spiro(indoline-3,4'-piperidin)-1'-yl)carbonyl)ethyl)-2-methylpropionamide monomethanesulfonate;Crescendo;MK-0677;UNII-R90JB6QJ2B;Propanamide, 2-amino-N-(2-(1,2-dihydro-1-(methylsulfonyl)spiro(3H-indole-3,4'-piperidin)-1'-yl)-2-oxo-1-((phenylmethoxy)methyl)ethyl)-2-methyl-, (R)-, monomethanesulfonate;
CAS Number	159752-10-0
Molecular Formula	CH₄O₃S*C₂₇H₃₆N₄O₅S
Molecular Weight	624.78
Boiling Point	868.9 °C at 760 mmHg
Flash Point	479.3 °C
PSA	196.66000
LogP	4.97440

What is MK-677 (159752-10-0) used for?

Ibutamoren, also known as MK-0677 or LUM-201, is a synthetic small-molecule GHSR agonist used as a growth hormone secretagogue in many disease settings. It wouldn't be all to involve MK 677 in the SARM category because it sort of resembles a peptide but is an HGH Secretagogue. In healthy elderly individuals, the oral administration of ibutamoren (MK-677), a non-peptide agonist of ghrelin receptors, increased serum growth hormone and IGF-1 levels without serious side effects.

InChIKey: DUGMCDWNXXFHDE-VZYDHVRKSA-N
InChI: InChI=1S/C27H36N4O5S.CH4O3S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27;1-5(2,3)4/h4-12,22H,13-19,28H2,1-3H3,(H,29,33);1H3,(H,2,3,4)/t22-;/m1./s1

Articles related to MK-677:

Article

Source

Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren (MK-677)

Heng Liu, Dapeng Sun, Alexander Myasnikov, Marjorie Damian, Jean-Louis Baneres, Ji Sun & Cheng Zhang

, Nature Communications volume 12, Article number: 6410 (2021)

Characterization of equine liver microsome-generated metabolites of growth hormone secretagogue small molecule ibutamoren (MK-677)

Moses Philip, Abdul Khader Karakka Kal, Michael Benedict Subhahar, Zubair Perwad, Tajudheen K. Karatt

, Rapid Communications in Mass Spectrometry, Volume35, Issue23 15 December 2021 e9201

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