Ivermectin

  • CasNo:70288-86-7
  • Molecular Formula:Unspecified
  • Purity:
  • Molecular Weight:875.09300
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Product Details

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What is the Ivermectin ?

Ivermectin is White crystalline powder, while it's Molecular Formula is Unspecified. Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Anthelmintic (Onchocerca). Ivermectin is a medication used to treat parasitic infections. It is derived from the avermectins, a class of highly active broad-spectrum antiparasitic agents. Ivermectin works by binding to specific receptors in the nervous systems of parasites, leading to paralysis and death of the parasites.

What is the CAS number for Ivermectin ?

The CAS number of Ivermectin is 70288-86-7.

More information of Ivermectin 70288-86-7 are:

Synonyms

Ivermectin EP6;

CAS Number

70288-86-7

Molecular Formula

Unspecified

Molecular Weight

875.09300

HS CODE

29322090

PSA

170.06000

LogP

5.60140

What is Ivermectin (70288-86-7) used for?

Ivermectin is an antiparasitic agent effective in the treatment of onchocerciasis, or "river blindness". Since ivermectin acts to prevent the adult worm from producing microfilariae, it needs to be administered only once or twice a year. It is used to treat a variety of parasitic infections in humans and animals, including head lice, scabies, river blindness, and intestinal worms. Ivermectin is available in tablet, cream, and lotion forms, and is generally considered safe and effective when used as directed. It has been widely used in mass drug administration programs to control parasitic infections in developing countries. In recent years, ivermectin has also been studied for its potential use in treating other conditions, such as COVID-19, although the evidence for its effectiveness in these applications is still limited. Overall, ivermectin is an important medication for the treatment of parasitic infections that has contributed to significant improvements in public health worldwide.

InChI:InChI=1/C48H74O14.C47H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38;1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3;11-14,18,24-25,27,29-30,32-44,48-49,51H,15-17,19-23H2,1-10H3/b13-12+,27-15+,32-14+;12-11+,26-14+,31-13+/t25?,26-,28-,30-,31-,33+,34?,35-,36-,37-,38?,39-,40+,41-,42-,43+,44-,45+,47+,48+;25-,27-,29-,30-,32+,33?,34-,35-,36-,37?,38-,39+,40-,41+,42-,43-,44+,46+,47+/m00/s1

Articles related to Ivermectin:

Article

Source

Randomized trial of metformin, ivermectin, and fluvoxamine for Covid-19

, The New England Journal of Medicine, 2022; 387:599-610

The adjusted odds ratio for hospitalization or death was 0.47 (95% CI, 0.20 to 1.11) with metformin, 0.73 (95% CI, 0.19 to 2.77) with ivermectin, and 1.11 (95% CI, 0.33 to 3.76) with fluvoxamine.

The Approved Dose of Ivermectin Alone is not the Ideal Dose for the Treatment of COVID-19

, Clinical Pharmacology & Therapeutics, Volume108, Issue4 October 2020 Pages 762-765

In summary, the likelihood of a successful clinical trial using the approved dose of ivermectin is low. Combination therapy should be evaluated in vitro.

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