Tadalafil 171596-29-5

  • CasNo:171596-29-5
  • Molecular Formula:C22H19N3O4
  • Purity:
  • Molecular Weight:
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Product Details

171596-29-5 Name

Name

Tadalafil

Synonym

TADALAFIL;CIALIS;IC 351;(6R,12AR)-6-(benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido;GF 196960;ICOS 351;Tildenafil;UK 336017

 

171596-29-5 Chemical & Physical Properties

Melting point 

298-300ºC

Boiling point

679.1±55.0 °C at 760 mmHg

Density

1.5±0.1 g/cm3

Molecular Formula

C22H19N3O4

Molecular Weight

389.404

Flash Point

364.5±31.5 °C

PSA

74.87000

LogP

1.43

Exact Mass

389.137543

Vapour Pressure

0.0±2.1 mmHg at 25°C

Index of Refraction

1.758

Storage condition

Hygroscopic, -20?C Freezer, Under Inert Atmosphere

 

171596-29-5 Description

Tadalafil is a PDE5 inhibitor with an IC50 value of 1.8 nM.IC50 Value: 1.8±0.4nM [1]Target: PDE 5Tadalafil is marketed in pill form for treating erectile dysfunction(ED) under the name Cialis, and under the name Adcirca for the treatment of pulmonary arterial hypertension. Tadalafil can elevate the level of cGMP in the corpus cavernosum and effectively improve ED of various causes and degrees.

 

171596-29-5 Uses

  1. Analgesic, norepinephrine uptake blocker, mu-opiod receptor agonist.A phosphodiesterase 5 inhibitor.Tadalafil is used for the treatment of erectile dysfunction.
  2. Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.