N-methyl pyrrolidone

  • CasNo:872-50-4
  • Molecular Formula:C5H9NO
  • Purity:
  • Molecular Weight:
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Product Details

872-50-4 Name

Name

N-methyl pyrrolidone

Synonym

M-PYROL(R);1-Methyl-2-pyrrolidinone( 99.5%, HyDry, Water≤50 ppm (by K.F.));1-Methyl-2-pyrrolidinone( 99.5%, HyDry, with molecular sieves, Water≤50 ppm (by K.F.));N-Methyl-2-pyrrolidone Manufacturer;1-METHYL-2-PYRROLIDONE, REAGENT (ACS)1-METHYL-2-PYRROLIDONE, REAGENT (ACS)1-METHYL-2-PYRROLIDONE, REAGENT (ACS);1-Methyl-2-pyrrolidinone 872-50-4 NMP N-Methyl-2-pyrrolidinone;N-Methyl-2-pyrrolidinone 872-50-4 NMP;1-METHYL-2-PYRROLIDINONE;N-Methylpyrrolidone NMP

 

872-50-4 Biological Activity

Description

N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an organic polar solvent. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals[1][2].

Related Catalog

Research Areas >> Others

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References

[1]. Jing Wang, et al. Nitrate stimulation of N-Methylpyrrolidone biodegradation by Paracoccus pantotrophus: Metabolite mechanism and Genomic characterization. Bioresour Technol. 2019 Dec;294:122185.

[2]. Claudia Julieta Solís-González, et al. Novel Metabolic Pathway for N-Methylpyrrolidone Degradation in Alicycliphilus sp. Strain BQ1. Appl Environ Microbiol. 2017 Dec 15;84(1):e02136-17.

 

872-50-4 Chemical & Physical Properties

Melting point 

−24 °C(lit.)

Boiling point

202.0±0.0 °C at 760 mmHg

Density

1.0±0.1 g/cm3

Molecular Formula

C5H9NO

Molecular Weight

99.131

Flash Point

86.1±0.0 °C

PSA

20.31000

LogP

-0.40

Exact Mass

99.068413

Vapour density

3.4 (vs air)

Vapour Pressure

0.3±0.4 mmHg at 25°C

Index of Refraction

1.470

Stability

Stable, but decomposes upon exposure to light. Combustible. Incompatible with strong oxidizing agents, strong acids, reducing agents, bases.

Water Solubility

>=10 g/100 mL at 20 ºC

 

872-50-4 Description

N-Methyl-2-pyrrolidone is an aprotic solvent with a wide range of applications: petrochemical processing, surface coating, dyes and pigments, industrial and domestic cleaning compounds, and agricultural and pharmaceutical formulations. It is mainly an irritant, but has also caused several cases of contact dermatitis in a small electrotechnical company.

 

872-50-4 Uses

  1. N-Methyl-2-pyrrolidone (NMP) is a polar aprotic solvent that has the advantages of low toxicity, high boiling point, outstanding solvency, strong selectivity and good stability. It is widely used in purification of aromatic hydrocarbon extraction, acetylene, olefins, and diolefins.
  2. It is used in industrial cleaning, and it serves as a solvent for production of pesticides, engineering plastics, coatings, synthetic fibers, and integrated circuits.
  3. It can also be used as an industrial cleanser, dispersant, dye, lubricant and antifreeze.
  4. N-Methyl-2-pyrrolidone is an excellent solvent, widely used in aromatics extraction, lubricating oil refining, acetylene enrichment, butadiene separation and synthesis gas desulfurization.
  5. It is used in gas desulfurization, lubricating oil refining, lubricating oil antifreeze, olefin extraction, and as a solvent for insoluble engineering plastics polymerization.
  6. It can be used in herbicide, to clean insulation materials, semiconductor industry precision instruments and circuit boards, to recycle PVC exhaust, as a detergent, dye supplement and dispersing agent.
  7. It is used in mediums for polymerization reactions such as engineering plastics and aramid fiber.
  8. N-Methyl-2-pyrrolidone is used as a polyvinylidene fluoride solvent and electrode auxiliary material for lithium ion batteries.
  9. High purity grade for ICP-MS detection.
  10. For peptide synthesis.