N'n-dicyclohexyl carbodiimide

  • CasNo:538-75-0
  • Molecular Formula:C13H22N2
  • Purity:
  • Molecular Weight:
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Product Details

538-75-0 Name

Name

N'n-dicyclohexyl carbodiimide

Synonym

Dicyclohexylcarbodiimide;N,N'-Dicyclohexylcarbodiimide [for Peptide Synthesis];N,N'-Dicyclohexylcarbodiimide, 0.1M sol.in DCM, peptide synthesis grade;N,N'-Dicyclohexylcarbodiimide, 1 M solution in dichloromethane;N,N'-Dicyclohexylcarbodiimide, 1M sol. In N-methylpyrrolidone,peptide synth.grade;N,N'-Dicyclohexylcarbodiimide,>98%;dcc solution;n,n'-dicyclohexylcarbodiimide solution;DCC Dicyclohexylcarbodiimide

 

538-75-0 Chemical & Physical Properties

Melting point 

34-35 °C(lit.)

Boiling point

122-124 ºC (6 torr)

Density

1.325

Molecular Formula

C13H22N2

Molecular Weight

206.327

Flash Point

87 ºC

PSA

24.72000

LogP

5.54

Exact Mass

206.178299

Vapour Pressure

0.0±0.5 mmHg at 25°C

Index of Refraction

1.567

Storage condition

Store at RT.

Stability

Stable, but moisture sensitive. Combustible. Incompatible with strong oxidizing agents. Avoid exposure to air or moisture.

Water Solubility

Reaction

 

538-75-0 Description

Dicydohexyl carbodiimide is used in peptide chemistry as a coupling reagent. It is both an irritant and a sensitizer, and caused contact dermatitis in pharmacists and chemists.

 

538-75-0 Uses

N,N'-Dicyclohexylcarbodiimide is a carbodiimide used to couple amino acids during peptide synthesis. N,N'-Dicyclohexylcarbodiimide is used as a dehydrating agent for the preparation of amides, ketones , nitriles as well as in the inversion and esterification of secondary alcohols.